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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1A
All Species:
11.82
Human Site:
T226
Identified Species:
21.67
UniProt:
O95602
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95602
NP_056240.2
1720
194811
T226
H
N
S
K
L
T
I
T
F
P
A
M
V
H
R
Chimpanzee
Pan troglodytes
XP_001135380
1723
195055
T226
H
N
S
K
L
T
I
T
F
P
A
M
V
H
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532976
1699
192037
T208
H
N
S
K
L
T
V
T
Y
P
A
M
V
H
K
Cat
Felis silvestris
Mouse
Mus musculus
O35134
1717
194092
K233
T
Y
P
A
T
V
H
K
K
S
D
Q
E
G
T
Rat
Rattus norvegicus
O54889
1716
194174
K233
T
Y
P
A
M
V
H
K
K
S
G
Q
K
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL98
1390
155685
D45
S
K
N
L
Y
S
Q
D
N
H
H
A
P
L
Q
Frog
Xenopus laevis
NP_001082182
1730
195193
S231
K
L
T
I
I
M
S
S
K
P
S
S
S
S
K
Zebra Danio
Brachydanio rerio
XP_001922839
1693
190636
E218
N
R
M
T
V
R
K
E
H
N
S
K
L
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91875
1642
185391
L224
V
R
Y
M
H
R
R
L
V
F
Y
V
T
L
A
Honey Bee
Apis mellifera
XP_001121092
1665
190473
Q210
N
L
S
N
E
T
I
Q
S
R
G
V
I
H
K
Nematode Worm
Caenorhab. elegans
NP_001022450
1737
195064
T282
G
G
G
G
A
E
V
T
G
D
V
V
D
L
D
Sea Urchin
Strong. purpuratus
XP_794863
1742
194988
I225
R
P
H
H
N
S
V
I
L
T
K
V
I
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10964
1664
186413
L284
K
Q
K
Q
A
K
K
L
D
G
S
N
E
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
90
N.A.
86.8
87.9
N.A.
N.A.
27
68.1
67.9
N.A.
43.7
43.6
39.3
46.8
Protein Similarity:
100
99.1
N.A.
94.4
N.A.
93.3
93.8
N.A.
N.A.
43.9
81.7
81.3
N.A.
61.4
61.5
57.4
64.4
P-Site Identity:
100
100
N.A.
80
N.A.
0
0
N.A.
N.A.
0
6.6
0
N.A.
0
26.6
6.6
0
P-Site Similarity:
100
100
N.A.
100
N.A.
0
6.6
N.A.
N.A.
20
40
26.6
N.A.
6.6
53.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
16
0
0
0
0
0
24
8
0
8
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
8
8
8
0
8
8
8
% D
% Glu:
0
0
0
0
8
8
0
8
0
0
0
0
16
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
16
8
0
0
0
0
0
% F
% Gly:
8
8
8
8
0
0
0
0
8
8
16
0
0
8
0
% G
% His:
24
0
8
8
8
0
16
0
8
8
8
0
0
31
0
% H
% Ile:
0
0
0
8
8
0
24
8
0
0
0
0
16
8
0
% I
% Lys:
16
8
8
24
0
8
16
16
24
0
8
8
8
0
24
% K
% Leu:
0
16
0
8
24
0
0
16
8
0
0
0
8
24
0
% L
% Met:
0
0
8
8
8
8
0
0
0
0
0
24
0
0
0
% M
% Asn:
16
24
8
8
8
0
0
0
8
8
0
8
0
0
0
% N
% Pro:
0
8
16
0
0
0
0
0
0
31
0
0
8
0
0
% P
% Gln:
0
8
0
8
0
0
8
8
0
0
0
16
0
0
8
% Q
% Arg:
8
16
0
0
0
16
8
0
0
8
0
0
0
0
16
% R
% Ser:
8
0
31
0
0
16
8
8
8
16
24
8
8
16
8
% S
% Thr:
16
0
8
8
8
31
0
31
0
8
0
0
8
0
8
% T
% Val:
8
0
0
0
8
16
24
0
8
0
8
31
24
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
16
8
0
8
0
0
0
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _